Dr.kalpana.

infection

Herpes simplex virus (HSV) is the most common infectious cause of corneal blindness in the Western Hemisphere, with up to 500,000 cases diagnosed annually in the United States alone. HSV is a multifaceted disease capable of inducing some of the most difficult management problems, including neurotrophic keratopathy. Herpetic neurotrophic keratopathy often presents with decreased corneal sensation and significantly impairs the ability of the corneal epithelium to heal itself after corneal injuries, leading to corneal ulcers in the absence of active virus. Neurotrophic keratopathy can also develop after Herpes Zoster (shingles) which leads to chronic epithelial disease and loss of vision. The persistence of decreased corneal sensation and its association with the degree of nerve damage in the cornea are still unknown.
In collaboration with Dr.Kalpana professor  of Ocular Virology, we are currently studying the nerve changes and cellular changes in herpetic disease. Through the use of the new state of the art HRT/RCM confocal microscope, which allows a revolutionary layer-by-layer analysis of the cornea and a magnification of up to 800 times, we are able to perform non-invasive examination of the cornea and obtain images of corneal layers and cells.