Wednesday 2 January 2013

Choroidal circulation related to myopic CNVMyopic macular degenerationMyopic choroidal neovascularisation (mCNV) may develop secondary to choroidal vascular insufficiency, according to a new study.High myopia is associated with excessive and progressive elongation of the globe, resulting in a variety of fundus changes that lead to visual impairment, including lacquer cracks in the Bruch membrane, choroidal neovascularization (CNV), and chorioretinal atrophy. The choroid is thin in highly myopic eyes and undergoes further attenuation with increasing age and increased myopia. Choroidal thinning may play a role in the pathophysiologic features of vision loss in high myopia. At some point relative ischemia of the outer retina, RPE, and the choroid itself may lead to pathologic decompensation.

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